Regional Emergency Planning Committees (REPCs) exist to enhance cooperative regional emergency planning. The Mystic REPC reviews and compiles procedures to deal with hazardous materials emergencies, trains first responders, and shares best practices with members and local businesses.

Under the Emergency Planning and Community Right-to-Know Act (EPCRA), Local Emergency Planning Committees (LEPCs) must develop an emergency response plan, review the plan at least annually, and provide information about chemicals in the community to citizens. Plans are developed by LEPCs with stakeholder participation. There is one LEPC for each of the more than 3,000 designated local emergency planning districts.